Study findings revealed that once-weekly subcutaneous semaglutide showed the largest estimated effect on body weight and several metabolic markers, identifying the GLP-1 RA as a highly promising intervention for future clinical trials in psychiatric populations, although comparative rankings remain uncertain because the evidence base was small, heterogeneous, and largely indirect
These medicines include injectable formulations such as semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and exenatide (Byetta, Bydureon BCise), as well as oral semaglutide (Rybelsus)
Unsaturated fats can also be beneficial for the heart
It is unknown whether glucagon will increase energy expenditure in humans and potentially spare lean mass, but this effect could influence body composition, in addition to a GIP effect for retatrutide
Focus on consistent, adequate hydration rather than extreme water consumption.