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Contrave, designed for oral administration, has variable bioavailability: naltrexone reaches about 96% bioavailability, while bupropion achieves approximately 87% bioavailability when taken with food

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doi: 10.1353/HPU.2011.0166 44 AlhomoudISTalasazAHChandrasekaranPBrownRMehtaADixonDL

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