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These varied treatment responses likely originate from our limited understanding of the mechanisms of weight regulation

Additionally, FOXO transcription factors have recently been implicated in tumorigenesis: in fact, rhabdomyosarcomas present FOXO genes with a high percentage of mutations that render them insensitive to inhibition by AKT signaling 65

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Studies have shown that the polyphenols and antioxidants present in yerba mate are responsible for its ability to enhance GLP-1 secretion