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Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications primarily approved by the FDA for managing type 2 diabetes mellitus and, in some cases, chronic weight management

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Similar trends were observed in a mouse model of pancreatic ductal adenocarcinoma (PDAC) ( LSL-Kras G12D/+ Trp53 f/f Pdx1 cre (KP / C) mice 28 ) and in humans with renal cell carcinoma 29 (Extended Data Fig