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FIGURE 1 2.4 Epileptic seizures monitoring Behavioral characterization was measured based on the modified Racines scale (Table 1) (Terzic et al., 2021) and PTZ injections were given every other day until the animals experienced two consecutive score 4 and 5 seizures, indicating the creation of a kindled model (Vasilev et al., 2018)

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579 In addition, metabolic disorders of neuronal Ca 2+ can drive ferroptosis through interactions with iron and crosstalk between the ER and mitochondria, and maintaining Ca 2+ homeostasis to inhibit ferroptosis may be an innovative target for the treatment of AD

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