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The Checkmate 214 phase 3 trial [10] looked at renal carcinoma patients receiving either double ICI agents or sunitinib and showed a similar positive outcome in both OS and improved QoL scores in the ICI group

As with any supplement, individual results vary, but consistent use is a common factor in the most positive outcomes

If approved on schedule, US patients could access it in early-to-mid 2027

This heterogeneity complicates the ability to draw definitive conclusions or recommend a standardized protocol mainly in preclinical models

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