The double-blinded, randomized control trial enrolled 72 adults with a BMI of 30 or higher who use automated insulin delivery systems to manage their type 1 diabetes
Clinical trials show Mazdutide delivers 14-20% weight loss without exercise
While delayed gastric emptying improves postprandial glycemic control and promotes satiety, it may also lead to prolonged gastric retention of solids and liquids, which has important clinical implications for patients undergoing procedures requiring sedation or anesthesia [3, 4]
Walking, swimming, or strength training all help improve insulin sensitivity and support weight loss
Majority of studies compared GLP-1RA to placebo [12, 14, 38,39,40, 44, 47, 48, 51,52,53,54,55,56,57,58,59,60,61], while others used insulin regiments and other anti-diabetic medications [41,42,43, 45,46,47, 49, 50] as the comparators