Figure 4 Due to the influence of renal clearance and dipeptidyl peptidase-4 (DPP-4), GLP-1 has a short natural half-life in the human body, about 12 min (113)
Retatrutide works similarly to tirzepatide in some ways, but it adds an additional metabolic target
Lotte Bjerre Knudsen (32:02): I don't know about health span, but because certainly there's been so many studies with metformin and there's been a lot of wonderful data showing an effect on the epigenetic clocks, but not really an effect on lifespan because that metformin is so widely used
MNT had the opportunity to speak with Anton Bilchik, MD, PhD, a surgical oncologist, chief of medicine and director of the Gastrointestinal and Hepatobiliary Program at Providence Saint Johns Cancer Institute in Santa Monica, CA, about this study
12 weeks 17 vials (10 mg) 84 daily doses needed