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If you are looking at B12 injections, the most useful starting point is the NHS treatment pathway, because it is built around how the body uses and stores B12 rather than around how often a top-up feels nice to have

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GLP-1/GIP receptor agonism versus NNMT enzyme inhibition

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Stack the two gaps together and the picture for the conventional protocol is unflattering: approximately one-fifteenth of the studied dose, delivered by a route that animal data suggest requires several-fold more peptide, targeting a compound whose dose-response may not be monotonic anyway