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Elevated serum B12 levels (hypercobalaminaemia) detected on blood tests may indicate underlying conditions such as liver disease, kidney dysfunction, or myeloproliferative disorders rather than representing a direct cause of symptoms

This non-selectivity is why it produces such a wide range of effects, from skin darkening to sexual arousal to appetite changes

Patients who took GLP-1 agonists for diabetes and weight loss experienced improvements in depressive symptoms, although the patients in those trials did not have clinical depression

This creates a dual problem: the meal stays in your system longer, and the FFAs themselves act as a brake on somatotroph function [6]