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JAMA Internal Med

frequently, these neurological fluctuations are directly tied to the inflammatory state of the gut following meals

No, it does not stimulate IGF-1 or muscle growth its effects are limited to fat metabolism pathways

Ghrelin acts on reward-related pathways by stimulating dopamine neurons in the ventral tegmental area and promoting dopamine turnover in the nucleus accumbens, a region of the ventral striatum (Xerfan et al., 2026), implicating that the anti-inflammatory properties of GLP-1 RAs could also be beneficial