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Emerging research explores its role in modulating glutamate levels, a neurotransmitter often imbalanced in individuals with ADHD

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The search strategy employed Boolean operators (e.g., AND, OR) to combine terms for natural flavonoid metabolites (e.g., quercetin, baicalin, epigallocatechin-3-gallate [EGCG]) with keywords related to AD and its underlying mechanisms, including skin barrier dysfunction, immune dysregulation, chemokine imbalance, pruritogenic signaling, microbial dysbiosis, programmed cell death, oxidative stress, and drug delivery

It is a complex mechanism

Lancet Diabetes & Endocrinology, 2021