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Notably, it has been reported that the gut microbes could metabolise tryptophan into tryptamine, kynurenine and indole derivatives involving the indoleamine 2,3-dioxygenase 1 (IDO1) and aryl hydrocarbon receptor (AHR) that have crucial roles in the immune homeostasis and tumour immune microenvironment respectively [247,248,249,250,251]

Introduction Research on the etiology of stress in college students who are studying health and engineering has gained importance in recent years because they are exposed to higher levels of stress than others (Kumar et al., 2019)