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A retest now of serum B12, once on weekly injections, will probably be unhelpful as it will be high either way
It is contraindicated in patients with certain mitochondrial disorders, porphyria, or fatty acid oxidation deficits
We order vitamin B12 and folate testing when a person with Down syndrome we are evaluating has symptoms described above, has a lab abnormality for which follow up testing of vitamin B12 and/or folate is indicated, or the person has a condition in which deficiency is common (e.g., celiac disease)
As a result, it serves as a model for studying fat metabolism and energy regulation in research contexts
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