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Both companies have requested the FDA add semaglutide and tirzepatide, respectively, to its lists of drug products that present demonstrable difficulties for compounding. These DDC Lists identify substances that are considered particularly risky to compound, and drugs on these lists cannot be compounded under either 503A or 503B which could be the biggest problem for companies like Hims

doi: 10.1159/000054522 20 StraderADBuntinJD

PLoS ONE 6 , e23367 (2011)

Mitochondrial glutathione transport is a key determinant of neuronal susceptibility to oxidative and nitrosative stress