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Selectivity of NNMT inhibitors Test compounds were screened in biochemical assays for activity against three structurally similar methyltransferases, including catechol-O-methyltransferase (COMT), DNA (cytosine-5)-methyltransferase 1 (DNMT1), and protein arginine methyltransferase 3 (PRMT3)
HumanRelevant Research Application
This is a compounded formulation dispensed as part of a supervised wellness protocol at Modern Wellness Clinic
89119 (Springer, 1990)
During the initial treatment period with methylcobalamin, pulmonary edema and congestive heart failure have reportedly occurred early in treatment with parenteral methylcobalamin
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