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Considerable potential A meta-analysis of randomized controlled trials, published last month in Annals of Internal Medicine , showed GLP-1 receptor agonists did not affect risk for multiple malignancies including colorectal cancer among adults with type 2 diabetes, or those with overweight or obesity

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The move reflects a broader trend as employers weigh the benefits of obesity treatment against rising healthcare expenses, raising concerns that access to popular weight-loss drugs could become more limited despite strong patient demand

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However, the specific impact of uric acid on NO levels in VSMCs remains elusive