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Similarly, although meal frequency was not explicitly tested in most trials, they say that strategies such as small, frequent meals may help reduce common side effects such as nausea and improve tolerability, especially in the early stages of treatment

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Reported side effects may include nausea, headache, and muscle spasms

Research in the American Journal of Physiology [5] demonstrates that GH pulsatility involves high-frequency secretory activity often missed by standard sampling