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This mechanism was validated by dapagliflozin (hypoglycemic agents) and atorvastatin (hypolipidemic agents) treatment in diabetic mice kidney and PA/high glucose-induced podocytes [69, 70]

Khoja L, Day D, and Wei-Wu Chen T, et al (2017) Tumour- and class-specific patterns of immune-related adverse events of immune checkpoint inhibitors: a systematic review Annals of Oncology 28 (10) 23772385 PMID: 28945858 44

These factors lead to the senescence of various cell types, including myoblasts, endothelial cells, and smooth muscle cells, thereby exacerbating conditions such as sarcopenia and vascular calcification (Troyano et al., 2015)

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