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GHK-Cus documented anti-inflammatory effects, including suppression of NF-kB signaling and reduction of TNF-alpha and IL-6 production, are mechanistically relevant to this area of research
Neuroprotection: Promotes nerve outgrowth and repair in experimental models
In the necrotic tissue of inflammation, ATP is released extracellularly to form extracellular ATP (eATP), which stimulates purinergic P2X receptor 7, thus activating inflammasome that drives an inflammatory response
doi: 10.3389/fimmu.2025.1740644 Received 06 November 2025 Revised 29 December 2025 Accepted 29 December 2025 Published 14 January 2026 Volume 16 - 2025 Edited by Zong Sheng Guo, University at Buffalo, United States Reviewed by Chi-Heng Wu, Dren Bio, Inc., United States Xingxing Yuan, Heilongjiang University of Chinese Medicine, China Updates Copyright 2026 Fan, Guo, Li, Wang, Bao, He and Jin
