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paper in Aesthetic Surgery Journal Open Forum (doi:10.1093/asjof/ojaf030) hypothesized that long-term GLP-1RA use may produce skin atrophy through a mechanism similar to glucocorticoid-induced thinning, citing the Nagae 2018 work and other in vitro evidence

Emerging research suggests they may even offer mental health benefits

Pinch the Skin: Gently pinch the skin at the injection site to create a small fold

GLP-1s are also covered for people with Type 2 diabetes

Patients with type 2 diabetes who also meet a Tier 2 or Tier 3 condition (such as HFpEF, CKD, prior heart attack, or stroke) and the corresponding BMI threshold may qualify under the Bridge for chronic weight management