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One of the main causes of decreased insulin secretion capacity in diabetes is oxidative stress

They could not be more different

Women with PCOS are prone to develop asthma while patients with asthma tend to exhibit increased susceptibility to metabolic syndrome, impaired fertility, irregular menstruation, and other clinical symptoms similar to PCOS [45]

Taking too little may not significantly support cellular glutathione levels, while unnecessarily high doses may offer diminishing returns, as the body can only utilize a limited amount at a time

It simply means your body may benefit more from pre-methylated forms of folate and B12