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Upon analysis of the kin-19 RNAi - dependent metabolic response, treated animals lacked the metabolic plasticity that was observed in wild-type or nhr-49(nr2041) animals

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Elevated levels of MAFG in astrocytes, through increased methylation and repression of target genes of nuclear erythroidderivedlike factor 2 (NRF2), which includes NFkB, have been shown to result in inflammation and increased oxidative stress

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