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Proteins were detected using an enhanced chemiluminescence system (Clinx Science Instruments, China)

Ozempic is designed for type 2 diabetes, while Wegovy is dedicated to weight management

0.33g of the crude Boc-His (Trt) -Aib-OSu and 1g of the compound 2 obtained in example 3 were dissolved in 20mL of N, N-dimethylformamide, 2mL of N, N-diisopropylethylamine was added, and the reaction was carried out at room temperature for 8 hours to obtain compound 4 with a purity of 74.08%, and a specific liquid phase diagram is shown in FIG

Verify compliance with regional regulations EU Cosmetic Regulation 1223/2009 documentation, FDA facility registration, and ASEAN cosmetic notification requirements where applicable