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The explanation for the discrepancy is likely to be that the antibody used by Gier et al 22 was not sufficiently specific, therefore eliciting questionable results

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[1] [2] These medications work by mimicking the action of natural GLP-1, binding to GLP-1 receptors throughout the body

Selection Bias: While baseline characteristics were generally well-balanced (24/24 Low risk), details regarding sequence generation (22/24 Unclear) and allocation concealment (24/24 Unclear) were largely missing, leading to a predominance of Unclear risk in the selection process