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This encourages general detoxification and helps liver function

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Treatment with a calcium channel blocker, benidipine, or an angiotensin type 1 receptor blocker, losartan, decreases blood pressure, reduces lipid accumulation in the kidneys, and increases the expression of carnitine palmitoyltransferase-1 143

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A sensitivity analysis excluding the ITCA trial yielded consistent results (HR (95%CI): 0.85 (0.770.94)