True hyperchromasia, coarse nuclear membranes, and chromatin clumping are rarely encountered in benign pigment cell lesions
10.1093/rb/rbx011 151 WangD.DengJ.DengX.FangC.ZhangX.YangP
Effects typically last 6 to 8 hours, sometimes extending to 12 hours
People differ in underlying biology and appetite regulation, and some are unable to reach or maintain higher doses [of current drugs] because of side effects, says Areesha Moiz, a clinical epidemiologist at the Lady Davis Institute for Medical Research in Quebec
Reported adverse reactions include nausea, difficulty breathing, and, in rare cases, serious conditions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and renal dysfunction