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When gut dysbiosisan imbalance in microbial diversitystrikes, it can breach intestinal permeability (aka leaky gut), allowing toxins and bacteria to leak into the bloodstream

WebMD Cited 10/11/2021

Although we have outlined recent insights of cGAS-STING in regulating IFN, inflammation, oxidative stress, autophagy and endoplasmic reticulum stress upon virus infections, this signalling axis is also involved in some other early host antiviral processes, such as different types of cell death and metabolism ( Figure 3 )

Grter T, Mohamad N, Rilke N, Blusch A, Sgodzai M, Demir S, et al