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10.2337/diabetes.48.5.1026 318 YousseifA.EmmanuelJ.KarraE.MilletQ.ElkalaawyM.JenkinsonA

Proper post-reconstitution storage can mean the difference between a vial that stays potent for its full life and one that degrades prematurely

Additionally, the impaired glucose metabolism seen in these conditions leads to the buildup of toxic advanced glycation end-products (AGEs), further damaging the peripheral nerves

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Rowbottom, L., Stinson, J., McDonald, R., Emmenegger, U., Cheng, S., Lowe, J., Giotis, A., Cheon, P., Chow, R., Pasetka, M., et al