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While urinary excretion of VC metabolites (oxalate, threonate) maintains systemic balance, prolonged deficiency ( ShacterEet alAscorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo

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For antioxidant and glutathione support, NAC is typically studied at 600-1,800 mg/day in divided doses

Indeed, neuronal activity itself can serve as a signaling mechanism that attracts oligodendrocyte precursors and stimulates remyelination [8,17,103,104]