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Paradoxically, a recent cross-sectional case control study comparing women with pre-eclampsia to healthy pregnant women at an obstetric visit during the third trimester observed that plasma LBP and zonulin levels were decreased in the women with pre-eclampsia compared with healthy controls (n = 44) [102]

In addition to exerting endothelial effects, GPER influences cardiovascular remodeling and function through the regulation of signaling molecules [10]

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