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Many of these species (about 45%) are herbivores by partly or completely feeding on plants and represent a significant proportion of pests or pollinators for economically important crops

10.1016/j.jep.2010.05.013 631

Active CASP8 cleaves BH3 interacting domain death agonist (BID) to generate truncated BID (tBID), thereby linking death receptor signaling to the mitochondrial pathway through BAX- and BAK1-mediated MOMP