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Jenkins et al., The analysis of proteins and their modifications benefits from continual advancements in liquid chromatography-tandem mass spectrometry (LC-MS/MS), a broadly used tool for proteomic investigations (Aebersold and Mann, 2015), data-dependent acquisition (DDA) (Mann et al., 2001), targeted multiple reaction monitoring (MRM) (Picotti and Aebersold, 2012