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Pharmacological management requires careful consideration in patients with diabetes: NSAIDs (such as ibuprofen or naproxen) are first-line when medication is needed and not contraindicated

The best time is from May to October, the dry season

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Tirzepatide, sold as Mounjaro and Zepbound, was not separately classified in the 2022 data and was not yet approved for weight management at that time, meaning it is not reflected in these figures

Genetics can affect appetite signaling, cravings, satiety, insulin response, fat storage tendencies, energy balance, inflammation, and how the body responds to certain metabolic interventions