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References [1] Yang B, Liu Y, Li Y, et al

This lower-dose formulation is often used as a starting or maintenance dose in long-term therapy

Psychostimulants have been reported to induce long-term extracellular and intracellular neurochemical damage primarily via glutamate-mediated pathways in dopaminergic reward systems, thereby modifying neuronal viability and neuroplasticity [31]