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Reduction of GSTP1 expression by DNA methylation correlates with clinicopathological features in pituitary adenomas

10.1517/14712598.4.12.1887 150 NagulaR

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For the majority of patients, gastrointestinal side effectsthe most common categorytypically peak during the first 48 weeks of treatment or following dose escalation, then gradually diminish over subsequent weeks as physiological adaptation occurs

It works as a dual GIP and GLP-1 receptor agonist , targeting two incretin hormones simultaneously