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If the answer to both is no, they will continue to up-titrate the dose by 2.5 mg every 4 weeks until reaching the next weight loss maintenance dose

The stumbling block has always been that it has to be given IV, in a clinic licensed for administration of intravenous drugs, in order to be effective

The discomfort is typically brief and well-tolerated by most individuals

Medical management is dominated by monotherapy with levothyroxine (LT4) for all HT conditions, as it is the only recommended treatment by the 2014 ATA and AACE guidelines