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We followed an iterative, hands-on process, strategizing, sketching, testing, and refining, until we landed on a wireframe that balanced form and function

Hmox-1 can also accelerate erastin-induced ferroptosis by generating ROS

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With the rise of Arabidopsis as a study system, and notably genome sequencing, the pathway and its genes were characterized at the molecular genetic level, revealing (or confirming) that all four enzymes were encoded by more than one gene, thus explaining the presence of the enzyme activities in several compartments (Table 1)

Treatment includes correcting identified nutritional deficiencies through supplementation and, in some cases, topical minoxidil