Increased levels of ROS and lipid peroxidation products and/or decreased levels of antioxidant enzymes, such as superoxide dismutase (SOD) and catalase, and antioxidant compounds, such as glutathione, have been reported in both NAFLD/NASH patients as well as a variety of animal models of NAFLD 9,10,11,12,13,14
Commonly reported observations include: Reduced joint stiffness, particularly morning stiffness Improved range of motion in affected joints Decreased reliance on anti-inflammatory medications Better tolerance of physical activity and exercise These clinical observations are valuable but represent anecdotal evidence
Reframing the Conversation How you communicate this to patients matters
Monitor pain using a 0-10 scale during and after activity Activity should not increase pain beyond baseline Post-activity soreness should resolve within 24 hours Watch for swelling or warmth returning to the injection site Pain escalating to 3-7/10 levels signals overload How Do You Increase Load Without Triggering A Flare-Up
The two are not alternatives
