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The demand for a safer, more selective growth hormone secretagogue prompted its development

The GCG gene is located on chromosome 2q24.2 and is composed of 6 exons

Furthermore, upon extensive evaluation of the downstream signaling of TGF-Beta 2, it was found that compared to nondiabetic mice, diabetic mice have increased expression of certain cardiac proteins, such as p-p38, a protein kinase activated by genotoxic stress [30], and even gene expression, such as connective tissue growth factor (CTGF), or CTGF which is involved in multiple pathologies [31]

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