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Glucose-dependent insulinotropic polypeptide receptor activation enhances the appetite suppressing effects of GLP-1 while adding unique metabolic benefits

980,981 A Phase 3, multicenter, randomized trial (EudraCT 2012-000353-31, NCT01825512) compared the efficacy of DFX and DFP in pediatric patients with transfusion-dependent haemoglobinopathies and found that DFP was more effective and safer in controlling iron overload than DFX over a 12-month treatment period

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The GAmelatoninbetaine combination produced the most notable and significant mitigation in IL-1 compared with other treatment combinations