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In the fox-odor container test, 3xTg mice exhibit increased predator odor-induced anxiety, which is detectable at 2 months of age (i.e., before the onset of AD pathology) and is more pronounced in aged females than males (Szab et al., 2023)

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In the PIONEER- 4 trial, semaglutide was not less effective than liraglutide at lowering HbA1c at its daily oral formulation dose [97]