This hormone plays a key role in controlling blood sugar levels and your feelings of hunger
In the STEP-1 trial of 1,961 adults (Wilding and colleagues, Once-Weekly Semaglutide in Adults with Overweight or Obesity, New England Journal of Medicine, 2021), participants on semaglutide 2.4 mg lost an average of 14.9 percent of their body weight at 68 weeks, compared to 2.4 percent on placebo
Finally, we reported causal effects indicating that the role of GLP-1 RAs in reducing the risk of depression and emotional instability may be mediated by BMI reduction, as shown in Figure 8
I.KutlarA.KanterJ.LilesD.CancadoR.FriedrischJ.et al (2017)
More precisely, for increasing skeletal muscle mass, volume is the key, where volume is define as (weight lifted per repetition, REPS)*(REPS per set)*(SETS)