The disorder usually presents in early childhood and is characterized by episodes of hypoketotic hypoglycemia (that can cause encephalopathy), hepatomegaly, elevated liver enzymes (transaminases), and hypoammonemia in infants
doi: 10.1016/j.trsl.2020.03.012, Summary Keywords aging, exercise, L-citrulline, leucine, musclevasculature, cognitive frailty, successful aging, neurovascular coupling Citation Lin X, Zhang Y, Pu J and Peng Y (2026) Targeting musclevasculature crosstalk in aging through the integrative roles of L-citrulline, leucine, and exercise: focus on muscle metabolism, vascular function, and sarcopenia prevention
Santiago JA, Potashkin JA
D-Penicillamine and trientine are used to treat Wilson disease because these agents facilitate copper excretion
doi:10.3390/biom12101407