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This complexity complicates the development of precise and effective therapies that can specifically modulate ferroptosis without disrupting other essential cellular processes

NAC directly replenishes intracellular glutathione, restoring feedback inhibition on the gamma-glutamyl cycle and reducing 5-oxoproline accumulation [6]

Based on outlier examination (random forest [RF] and principal component analysis [PCA]), no samples were categorized as outliers, and all data were retained for subsequent analysis

Arora S, Santiago JA, Bernstein M, Potashkin JA

Lower concentrations would push injection volumes uncomfortably high