does semaglutide affect immune system GLP-1 drugs calm inflammation beyond diabetes and weight loss Semaglutide and Inflammation | Lux

In one study, people using Wegovy lost approximately 15% of their body weight over 68 weeks (approximately 16 months)

[DOI] [PMC free article] [PubMed] [Google Scholar] Szabo C, Ransy C, Modis K, Andriamihaja M, Murghes B, Coletta C et al (2014)

The most helpful way to look at it is as a medically guided tool that can make healthy changes more achievable, not unnecessary

Data from the STEP [52] and SUSTAIN [53, 54] trials consistently demonstrate that the substantial weight loss achieved with semaglutide at doses of 0.5 mg, 1.0 mg, and 2.4 mg is largely independent of these symptoms, with less than 1% of the total weight loss benefit attributable to GI AEs

Psychiatric adverse events were rare, with two reported in the semaglutide alone group, one in the nimacimab alone group and one in the placebo group