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Regenerative & Advanced Therapies For persistent or recurrent cases, additional modalities may be recommended: Shockwave Therapy : May accelerate healing in chronic PFPS Image-guided Injection (rare) : In select severe cases, injection treatment may reduce pain and support rehab Surgery is rarely needed, reserved only for cases with structural joint abnormalities or failed conservative care

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By day seven, most patients notice appetite suppression beginning to fade, which is why weekly injections maintain steady therapeutic levels rather than daily dosing

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Conversely, discontinuation rates were increased to 28.1% (95% CI 27.7, 28.4) at 1 year and 43.6% (95% CI 43.2, 44.0) at 3 years when using a grace period of 60 days (ESM Table 4)