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Chey WD, Leontiadis GI, Howden CW, Moss SF (2017) ACG clinical guideline: treatment of Helicobacter pylori infection

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This is particularly important if: Symptoms are affecting your daily life or quality of sleep You're experiencing severe or sudden allergic reactions Over-the-counter antihistamines aren't providing relief You suspect your symptoms are linked to your menstrual cycle or hormonal changes You're considering HRT and want to discuss the histamine connection Ask your GP specifically about the relationship between hormones and histamine