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For patients with a BMI over 40, or those with serious conditions like type 2 diabetes, sleep apnea, or joint disease, bariatric surgery remains the most effective and durable treatment we have

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Maintaining adequate hydration is important, especially if experiencing gastrointestinal side effects, to reduce the risk of dehydration and acute kidney injury

Pregnancy, Surgical Planning, and Other Contraindications Both semaglutide and tirzepatide are contraindicated during pregnancy

The medication's long half-life of approximately one week allows for once-weekly dosing and sustained action between injections