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Most ProFractional patients find the treatment doesnt warrant numbing, though it can be used

The term Depo-Medrol usually refers to the 40 mg/mL or 80 mg/mL methylprednisolone acetate suspension

To prevent this, use the smallest gauge needle practical for drawing doses (29-31 gauge insulin needles), always insert the needle straight (not at an angle), and try to puncture the same spot on the stopper each time rather than creating new holes across the surface

short 2.5 mg cohort about -4.7% at ~4 weeks, -12.7% by the 5 mg phase (Barrea 2026): Mody Diabetes Ther 2025

Maintaining healthy levels of B12 in the body prevents anemia